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Following the discovery that nicotine alters the expression of the PRM1 and PRM2 genes, further studies were conducted to investigate whether various nicotine products, such as smoking and hookah, had a different impact on the expression of these protamines [86, 96, 97, 104, 105, 106]

Percentage of students who report vaping marijuana recently, (based on the 2023 Monitoring the Future survey): 8th grade 7% of students reported vaping marijuana in the past year

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