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It was a philosophy of patient, incremental reward that resonated enormously with the generation that had grown up during the Depression and the war years, people who understood in their bones what it meant to save carefully toward a specific goal

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Variants at the 15q25 locus have been confirmed by several studies associated with increased tobacco addiction and lung cancer risk [47, 48], but a significant gene-environment interaction is controversial [50, 51]

And then it was smooth sailing: by the end of the 1990s, more than 95% of cigarettes worldwide had filters

----- Woody Allen films have always been a favorite of mine