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Sulfated glycosaminoglycans in decellularized placenta matrix as critical regulators for cutaneous wound healing

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The dosage of supplementation in these studies ranged from 2.5 to 1000 mg daily for up to 6.5 months, with sources including Saccharomyces cerevisiae, Aureobasidium pullulans, Pleurotus ostreatus, Lentinula edodes and Ganoderma lucidum 6

doi: 10.1038/s41577-019-0248-y 37 BhatiaSNIngberDE

A similar mechanism has been observed in endothelial cells, where 1,25(OH)D attenuates inflammatory activation and p38 MAPK signaling, thus protecting against apoptosis and the release of pro-inflammatory mediators [204]