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Likewise, BPC 157s therapeutic healing effects occurred to ameliorate against all adverse effects related to the crush injury as external mechanical pressure, including the counteraction of the increased enzyme activity (creatinine kinase, lactate dehydrogenase, aspartate aminotransferase, alanine aminotransferase) [45]

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Global sensitivity analysis revealed that k 02 (oxygen concentration) is the most sensitive parameter for OCR and ROS output, suggesting that biological environments with elevated oxygen presence could be more susceptible to redox-induced ROS