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PMCID: PMC10159235
Li FJHZ, Long ZW, Zhou HY, Luo SG, Xu LC, Gao
doi: Compliance Statement This product is intended for laboratory research use only and is not approved for human or veterinary use.
Based on the aforementioned studies, we were motivated in this experimental model to investigate the possible protective effects of EMPA pretreatment (1 and 3 mg/kg) against PTZ-induced seizures in rats using the win-PTZ kindling method and to figure out the mechanism that may underlie its antiepileptic effect and the implication of the BDNF pathway in an attempt to provide a new therapeutic venue for EMPA as a neuroprotective drug that may target the process of epileptogenesis
doi: 10.1016/j.redox.2021.101947 43 UrsiniFMaiorinoM
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