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Further research is essential to fully realize their potential and ensure safe, effective deployment in managing diabetes and its complications

FIGURE 1 2.1 Iron metabolism imbalance Iron, an essential trace element, primarily participates in metabolic processes in the forms of Fe 2+ and Fe 3+ ( 2+ absorbed in the intestines or released from erythrocyte degradation is oxidized to Fe 3+ by ceruloplasmin (CP) in the circulation

On the other hand, certain studies have demonstrated the overexpression of GLP-1R in brain tumors, embryonic tumors, gut and lung neuroendocrine tumors, including other endocrine tumors like Pheochromocytomas, raising concerns that existing GLP-1RAs can contribute to tumor growth in humans (Korner et al., 2007

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