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available at Ethics statement The animal study was approved by the Ethics Committee of Shandong Rongjun General Hospital (No: RY00006)

One of the advantages of glutathione IM injections is the minimal to non-existent downtime associated with the procedure

The nuclear glutathione pool is more resistant to depletion by BSO than the cytosolic as it was demonstrated in 3T3 fibroblasts and other human cell lines 87,88 , hence we cannot exclude the possibility that AITC -which presumably acts differently from BSO- is able to deplete efficiently the nuclear pool

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Additionally, do not switch between medications immediately