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It decreases COX-2 gene expression, reduces myeloperoxidase activity, and lowers pro-inflammatory cytokines including IL-6 and TNF-alpha

This mechanism promotes the formation of new blood vessels and muscle tissue fibers, accelerating recovery from injuries

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Comment: While many commenters indicated that our proposed changes to the HPT requirements outlined in the CY 2026 OPPS/ASC proposed rule and/or the HPT requirements in general are burdensome, as discussed in prior sections of this final rule with comment period, only several commenters commented on our specific burden estimates for these information collections