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Mechanistically, coculture systems have demonstrated in EVCs and macrophages stimulated by CCL5/CCR1/CCR5 that axis-mediated BC cell growth and migration were independent of one another

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As will be explained in Chapters 3 and 5, the committee believes that a substantial portion of the declines in smoking prevalence and smoking intensity over the past 25 years is attributable to tobacco control interventions, especially price increases and the emergence of a strong antismoking social norm

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