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Patches absorb slowly through the skin, so they work better for mild support rather than treating serious deficiency

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Skin Repair Pathways MMP/TIMP, Collagen & Elastin (PMC, 2015) A focused review of GHK as a modulator of multiple skin regeneration pathways published in PMC confirmed that GHK-Cu stimulates both synthesis and breakdown of collagen and glycosaminoglycans, and modulates the activity of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs)

These drugs can increase risk of serious infection and cancer (NIH 2013

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